韩国成
学术学位博导
***
***
生命与环境科学学院
个人简介

韩国成,教授,博士生导师,曾在加拿大访学1年,主要从事生物传感器和电分析化学的研究工作。主持国家自然科学基金地区项目2项,主持完成国家自然科学基金青年基金项目1项,主持广西区自然科学基金青年基金和面上项目各1项。共发表SCI论文80余篇,其中通讯作者或第一作者论文70篇,全部论文SCI他引700余次;获2项授权发明专利,获省部级自然科学奖二等奖2项。中国化学会、中国自动化学会、中国生物医学工程学会健康工程分会委员,担任MPDI数据库审稿专家,Sustainability客座编辑2018入选广西高等学校千名中青年骨干教师培育计划”人选,承担基因组学、专业英语、生物化学、普通化学,高等分子生物学等课程教学。

 

论文情况

2024

[79] F. L. Chen, K. H. Song, J. T. Xu, K. Z. Wang, X. Z. Feng, G. C. Han, H. B. Kraatz, An electrochemical aptamer sensor for rapid quantification sulfadoxine based on synergistic signal amplification of indole and MWCNTs and its electrooxidation mechanism, Sensors and Actuators B: Chemical, 2024, 401, 135008.

[78] Q. Q. An, X. Z. Feng, T. Zhan, Y. Y. Cheng, G. C. Han, Z. Chen, H. B. Kraatz, A simple synthesis of a core-shell structure PPy-Au nanocomposite for immunosensing of C-reactive protein, Talanta, 2024, 267, 125158.

[77] C. W. Shan, Z. Chen, G. C. Han, X. Z. Feng, H. B. Kraatz, Electrochemical immuno-biosensors for the detection of the tumor marker alpha-fetoprotein: A review, Talanta, 2024, 271, 125638.

[76] Y. T. Xue, Z. Chen, X. Chen, G. C. Han, X. Z. Feng, H. B. Kraatz, Enzyme-free glucose sensor based on electrodeposition of multi-walled carbon nanotubes and Zn-based metal framework-modified gold electrode at low potential, Electrochimica Acta, 2024, 483, 144009.

[75] B. Zhao, Z. Chen, G. C. Han, X. Z. Feng, H. B. Kraatz, Carbon-based electrochemical sensor: Modified electrodes and as-prepared 3D printed electrodes for simultaneous detection of purines and pyrimidines, Microchemical Journal, 2024, 197, 109894. 


2023

[74] X. Chen, X. Z. Feng, T. Zhan, Y.-T. Xue, H. X. Li, G. C. Han, Z. Chen, H.-B. Kraatz, Construction of a portable enzyme-free electrochemical glucose detection system based on the synergistic interaction of Cu-MOF and PtNPs, Sensors and Actuators B: Chemical, 2023, 395, 134498.

[73] T. Zhan, X. Z. Feng, Y. Y. Cheng, G. C. Han, Z. Chen, H. B. Kraatz, Electrochemical sensor for ultrasensitive sensing of biotin based on heme conjugated with gold nanoparticles and its electrooxidation mechanism, Food Chemistry, 2023, 429, 136997.

[70] X. Y. Wang, Y. J. Lv, X. F. Kong, Z. Y. Ding, X. Cheng, Z. Liu, G. C. Han, A fluorescence visual detection for glyphosine based on a biomass carbon quantum dot paper-based sensor, New Journal of Chemistry, 2023, 47, 10696-10705.

[69] J. Z. Wan, G. C. Han, A Facile Sensor for Detection of Lysozyme in Egg White Based on AuNPs and Ferrocene Dicarboxylic Acid, Chemosensors, 2023, 11, 209.

[68] C. W. Shan, X. Z. Feng, G. C. Han, Z. C. Chen, H. B. Kraatz, Synergistic Amplification Signal Based on CoNPs and Melamine for Simultaneous Quantification of Epinephrine and Serotonin, Journal of the Electrochemical Society, 2023, 170, 017509.

[67] R. Q. Huang, W. Li, X. L. Luo, Z. Liu, G. C. Han, R. Z. Wei, Synthesis, crystal structure and properties of Mn/Ni/Co 3D network structures based on 2, 5-bis(trifluoromethyl) terephthalic acid ligands, Inorganica Chimica Acta, 2023, 557, 121672.

[66] R. T. Guo, W. Li, X. Y. Wang, Y. J. Lv, M. Q. Chen, Z. S. Chen, Z. Liu, G. C. Han, Antimicrobial corrosion study of the epoxy coating with the graphene oxide supported Schiff base quaternary ammonium salt additives, Materials Today Communications, 2023, 35, 105517.

[65] R. T. Guo, W. Li, R. Q. Huang, M. Q. Chen, Z. Liu, G. C. Han, Shuttle-inhibited 3D sandwich MXene/SnO2QDs sulfur host for high- performance lithium-sulfur batteries, Journal of Alloys and Compounds, 2023, 937, 168427.

[64] Y. Y. Cheng, X. Z. Feng, T. Zhan, Q. Q. An, G. C. Han, Z. C. Chen, H. B. Kraatz, A facile indole probe for ultrasensitive immunosensor fabrication toward C-reactive protein sensing, Talanta, 2023, 262, 124696.

 

2022

[63] Z. F. Zhou, X. Z. Feng, T. Zhan, G. C. Han, Z. C. Chen, H. B. Kraatz, Facile bimetallic co-amplified electrochemical sensor for folic acid sensing based on CoNPs and CuNPs, Analytical and Bioanalytical Chemistry, 414(2022) 6791-6800.

[62] T. Zhan, X. Z. Feng, Y. Y. Cheng, G. C. Han, Z. C. Chen, H. B. Kraatz, Synergistic Electrochemical Amplification of Ferrocene Carboxylic Acid Nanoflowers and Cu Nanoparticles for Folic Acid Sensing, Journal of the Electrochemical Society, 169(2022).

[61] T. Zhan, X. Z. Feng, Q. Q. An, S. Y. Li, M. Y. Xue, Z. C. Chen, et al., Enzyme-free glucose sensors with efficient synergistic electro-catalysis based on a ferrocene derivative and two metal nanoparticles, Rsc Advances, 12(2022) 5072-5079.

[60] R. Z. Wei, Z. Liu, W. C. Wei, S. Wang, Y. J. Lv, G. C. Han, Anticorrosion performance of hydrophobic acid-modified-MOFs/epoxy coatings, Colloid and Interface Science Communications, 46(2022).

[59] S. Wang, R. Q. Huang, W. Li, Y. J. Lv, G. C. Han, R. Z. Wei, et al., Synthesis, structure and properties of two complexes based on N and S heterocyclic dicarboxylic acid ligands, Molecular Crystals and Liquid Crystals, (2022).

[58] D. Sun, R. T. Guo, Y. J. Lv, W. Li, M. J. Lu, Q. M. Wei, et al., Na2MnPO4F/Ti3C2-CQDs composite cathode material with enhanced electrochemical properties for lithium/sodium hybrid ion battery, Diamond and Related Materials, 128(2022).

[57] Q. M. Lin, X. Z. Feng, F. L. Chen, K. H. Song, G. C. Han, Z. C. Chen, et al., A Novel Electrochemical Strategy for Chloramphenicol Detection in a Water Environment Based on Silver Nanoparticles and Thiophene, Journal of the Electrochemical Society, 169(2022).

[56] R. T. Guo, W. Li, M. J. Lu, Y. J. Lv, H. T. Ai, D. Sun, et al., Na3V2(PO4)(2)F-3@bagasse carbon as cathode material for lithium/sodium hybrid ion battery, Physical Chemistry Chemical Physics, 24(2022) 5638-5645.

[55] Q. Q. An, X. Z. Feng, Z. F. Zhou, T. Zhan, S. F. Lian, J. M. Zhu, et al., One step construction of an electrochemical sensor for melamine detection in milk towards an integrated portable system, Food Chemistry, 383(2022).

[54] D. Sun, W. Li, R. T. Guo, Q. Q. Liang, Z. Liu, G. C. Han, Preparation of N-doped biomass C@SnO2 composites and its electrochemical performance, Diamond and Related Materials, 120(2021).

[53] J. G. Liu, J. Z. Wan, Q. M. Lin, G. C. Han, X. Z. Feng, Z. C. Chen, Convenient Heme Nanorod Modified Electrode for Quercetin Sensing by Two Common Electrochemical Methods, Micromachines, 12(2021).

 

2021

[52] Y. Y. Cheng, T. Zhan, X. Z. Feng, G. C. Han, A synergistic effect of gold nanoparticles and melamine with signal amplifification for C-reactive protein sensing, Journal of Electroanalytical Chemistry, 895(2021) 115417.

[51] R. Z. Wei, Z. Liu, W. C. Wei, C. X. Liang, G. C. Han, L. Zhan, Synthesis, Crystal Structure and Characterization of Two Cobalt (II) Complexes Based on Pyridine Carboxylic Acid Ligands, Zeitschrift Fur Anorganische Und Allgemeine Chemie, (2021).DOI: 10.1002/zaac.202000418

[50] W. C. Wei, Z. Liu, R. Z. Wei, C. X. Liang, X. Z. Feng, G. C. Han, Synthesis, crystal structure and anticorrosion performance of Zn(II) and Ni(II) complexes, Journal Of Molecular Structure, 1228(2021) 129452.

[49] Z. S. Chen, K. H. He, R. Z. Wei, Y. J. Lv, Z. Liu, G. C. Han, Synthesis of Mn-MOFs loaded zinc phosphate composite for water-based acrylic coatings with durable anticorrosion performance on mild steel, Rsc Advances, 11(2021) 3371-3379.

[48] H. T. Ai, W. Li, Z. Liu, D. Sun, H. Z. Zhou, G. C. Han, A new lithium-ion batteries derivated from waste bagasse: Preparation, characterization and application, Journal Of Alloys And Compounds, 854(2021) 157156.

 

2020

[47] W. C. Wei, Z. Liu, R. Z. Wei, G. C. Han, C. X. Liang, Synthesis of MOFs/GO composite for corrosion resistance application on carbon steel, Rsc Advances, 10(2020) 29923-29934.

[46] W. C. Wei, Z. Liu, C. X. Liang, G. C. Han, Y. K. Li, Q. W. Li, et al., Corrosion Inhibition Performance of Nitrogen-Containing Metal Organic Framework Compounds on Copper Flakes in Dilute HCl Medium, Protection Of Metals And Physical Chemistry Of Surfaces, 56(2020) 638-650.

[45] W. C. Wei, Z. Liu, C. X. Liang, G. C. Han, J. X. Han, S. F. Zhang, Synthesis, characterization and corrosion inhibition behavior of 2-aminofluorene bis-Schiff bases in circulating cooling water, Rsc Advances, 10(2020) 17816-17828.

[44] G. C. Han, H. F. Li, A. Ferranco, T. Zhan, Y. Y. Cheng, Z. C. Chen, et al., The construction of a simple sensor for the simultaneous detection of nitrite and thiosulfate by heme catalysis, Rsc Advances, 10(2020) 35007-35016.

[43] X. Z. Feng, X. R. Su, A. Ferranco, Z. C. Chen, G. C. Han, Z. L. Jiang, et al., Real-Time Electrochemical Detection of Uric Acid, Dopamine and Ascorbic Acid by Heme Directly Modified Carbon Electrode, Journal Of Biomedical Nanotechnology, 16(2020) 29-39.

[42] X. Z. Feng, H. F. Li, A. Ferranco, Z. C. Chen, M. Y. Xue, G. C. Han, et al., A Very Simple Method for Detection of Bisphenol A in Environmental Water by Heme Signal Amplification, Journal Of the Electrochemical Society, 167(2020) 067503.

[41] L. L. Cao, G. C. Han, H. L. Xiao, Z. C. Chen, C. Fang, A novel 3D paper-based microfluidic electrochemical glucose biosensor based on rGO-TEPA/PB sensitive film, Analytica Chimica Acta, 1096(2020) 34-43.

 

2019

[40] Q. Q. Liang, Z. Liu, C. X. Liang, G. C. Han, S. F. Zhang, X. Z. Feng, Electrochemical Simultaneous Detection of Paracetamol and 4-aminophenol Based on bis-Schiff Base Cobalt Complex, International Journal Of Electrochemical Science, 14(2019) 7178-7201.

[39] C. X. Liang, Z. Liu, Q. Q. Liang, G. C. Han, J. X. Han, S. F. Zhang, et al., Synthesis of 2-aminofluorene bis-Schiff base and corrosion inhibition performance for carbon steel in HCl, Journal Of Molecular Liquids, 277(2019) 330-340.

[38] G. C. Han, X. R. Su, J. T. Hou, A. Ferranco, X. Z. Feng, R. S. Zeng, et al., Disposable electrochemical sensors for hemoglobin detection based on ferrocenoyl cysteine conjugates modified electrode, Sensors And Actuators B-Chemical, 282(2019) 130-136.

[37] X. Z. Feng, A. Ferranco, X. R. Su, Z. C. Chen, Z. L. Jiang, G. C. Han, A Facile Electrochemical Sensor Labeled by Ferrocenoyl Cysteine Conjugate for the Detection of Nitrite in Pickle Juice, Sensors, 19(2019) 268.

[36] Z. C. Chen, Y. Bai, F. J. Zhao, L. L. Cao, G. C. Han, S. M. Yin, Disposable Amperometric Immunosensor for Hepatitis B Antigen Detection Based on Multiwalled Carbon Nanotubes and Ferrocene Decorated Screen Printed Electrode, Journal Of Biomedical Nanotechnology, 15(2019) 930-938.

 

2018

[35] L. Zheng, J. X. Han, H. Y. Li, G. C. Han, Z. N. Guo, S. F. Zhang, et al., Synthesis, crystal structure and properties of rare earth metal-organic framework materials based on the 2,5-pyridinedicarboxylic acid ligands, Molecular Crystals And Liquid Crystals, 666(2018) 109-118.

[34] F. J. Zhao, Y. Bai, R. S. Zeng, L. L. Cao, J. M. Zhu, G. C. Han, et al., An Electrochemical Immunosensor with Graphene-Oxide-Ferrocene-based Nanocomposites for Hepatitis B Surface Antigen Detection, Electroanalysis, 30(2018) 2774-2780.

[33] H. Wang, Z. Liu, Q. Q. Liang, H. Y. Zhong, G. C. Han, S. F. Zhang, et al., A facile method for preparation of doped-N carbon material based on sisal and application for lead-carbon battery, Journal Of Cleaner Production, 197(2018) 332-338.

[32] H. Wang, Z. Liu, Q. Q. Liang, G. C. Han, P. Guo, X. Q. Lao, et al., Electrocatalytic Oxidation of L-cysteine by Adamantane Ester Schiff Base Nickel Complexes, International Journal Of Electrochemical Science, 13(2018) 10454-10469.

[31] H. Wang, Z. Liu, H. Y. Li, G. C. Han, L. Yun, H. Y. Zhong, Electrochemical Performance of Lead-Carbon Battery with Chitosan Composite Carbon/Lead Negative Plate, International Journal Of Electrochemical Science, 13(2018) 136-146.

[30] G. C. Han, X. R. Su, J. T. Hou, X. Z. Feng, Z. C. Chen, Interaction Study of Fc(COOH)(2) and BSA by UV-Vis Spectroscopy, Spectroscopy And Spectral Analysis, 38(2018) 3958-3962.

 

2017

[29] Y. Xing, X. Z. Feng, L. P. Zhang, J. T. Hou, G. C. Han, Z. C. Chen, A sensitive and selective electrochemical biosensor for the determination of beta-amyloid oligomer by inhibiting the peptide-triggered in situ assembly of silver nanoparticles, International Journal Of Nanomedicine, 12(2017) 3171-3179.

[28] H. Y. Li, Z. Liu, H. Wang, G. C. Han, Y. Zhao, S. W. Xie, et al., Molecular Dynamics Simulation of Adsorption Behavior of Schiff base Gemini Surfactants on Zn (110) Surface, International Journal Of Electrochemical Science, 12(2017) 6622-6637.

[27] J. X. Han, Z. Liu, Y. J. Guo, G. C. Han, W. Li, S. Y. Chen, et al., Determination of superoxide anion radical by modified CdTe quantum dots, Journal Of Photochemistry And Photobiology a-Chemistry, 349(2017) 1-6.

[26] G. C. Han, J. T. Hou, Z. L. Huang, X. Z. Feng, Z. C. Chen, W. X. Xiao, et al., Electrochemical Behaviors of Ferrocene Dicarboxylate and its Application for Heme Detection, International Journal Of Electrochemical Science, 12(2017) 6245-6254.

 

2016

[25] J. Zhang, Z. Liu, G. C. Han, S. L. Chen, Z. C. Chen, Inhibition of copper corrosion by the formation of Schiff base self-assembled monolayers, Applied Surface Science, 389(2016) 601-608.

[24] R. S. Zeng, Z. G. Sun, C. J. Zhou, C. Fang, G. C. Han, Z. C. Chen, Well-resolved oil-soluble Au-doped ZnCdS quantum dots and enhancing doping emission with In-codoping, Journal Of Alloys And Compounds, 671(2016) 66-73.

[23] Z. Liu, Y. Zhao, G. C. Han, J. Liu, Q. Y. He, C. Z. Chen, Preparation of Schiff base surfactant and its application in alkaline zinc-nickel batteries, Ionics, 22(2016) 2391-2397.

[22] M. La, Y. Q. Hao, Z. Y. Wang, G. C. Han, L. B. Qu, Selective and Sensitive Detection of Cyanide Based on the Displacement Strategy Using a Water-Soluble Fluorescent Probe, Journal Of Analytical Methods In Chemistry, 2016(2016) 1462013.

[21] G. C. Han, J. T. Hou, X. Z. Feng, Z. L. Huang, W. Gu, Z. C. Chen, Electrochemical Determination of Protease with Improving Sensitivity by Electrochemical-chemical-chemical Redox Cycling, International Journal Of Electrochemical Science, 11(2016) 8646-8653.

[20] G. C. Han, X. Z. Feng, J. T. Liang, W. X. Xiao, Z. C. Chen, Interaction Study of Ferrocene Derivatives and Heme by UV-Vis Spectroscopy, Spectroscopy And Spectral Analysis, 36(2016) 1585-1591.

[19] Y. J. Guo, Z. Liu, G. C. Han, W. Li, Y. J. Hu, Z. C. Chen, A New Fluorescent Switch for Determination of Pb2+ Based on Modified CdTe Quantum Dots, Journal Of Nanoscience And Nanotechnology, 16(2016) 12172-12178.

[18] X. Z. Feng, G. C. Han, J. H. Qin, S. M. Yin, Z. C. Chen, Determination of Residual Solvents in Linezolid by Static Headspace GC, Journal Of Chromatographic Science, 54(2016) 487-491.

 

2015

[17] X. Y. Zhao, W. Liu, B. B. Zhou, S. S. Liu, G. C. Han, Electrochemical MicroRNAs Biosensors Based on Enzymatic Signal Amplification, International Journal Of Electrochemical Science, 10(2015) 8910-8925.

[16] S. W. Xie, Z. Liu, G. C. Han, W. Li, J. Liu, Z. C. Chen, Molecular dynamics simulation of inhibition mechanism of 3,5-dibromo salicylaldehyde Schiff's base, Computational And Theoretical Chemistry, 1063(2015) 50-62.

[15] L. Y. Lai, Z. Liu, G. C. Han, Z. C. Chen, Synthesis, Crystal Structure and Properties of Three Metal Complexes Based on a Flexible Schiff Base Ligand, Journal Of Cluster Science, 26(2015) 1845-1855.

[14] L. Y. Lai, Z. Liu, G. C. Han, Crystal structure of {4,4 ',6,6 '-tetrabromido-2,2-[ethane-1,4-diyl(nitrilomethanylylidene)-1-ethylamine-2-methoxyl]diphenolato-kappa O-5,N,N ',N '',O '} zinc(II) - dimethylformamide (2:1), C41H45Br8N7O7Zn2, Zeitschrift Fur Kristallographie-New Crystal Structures, 230(2015) 189-191.

[13] G. C. Han, X. Z. Feng, Z. C. Chen, Hemin/G-quadruplex DNAzyme for Designing of Electrochemical Sensors, International Journal Of Electrochemical Science, 10(2015) 3897-3913.

 

2014

[12] Z. Liu, W. Li, G. C. Han, S. Yuan, Z. C. Chen, Towards Label-Free Impedance Biosensors: CRP Probe Based on Thiol Schiff-Nickel Complex Modified Gold Nanoparticles, Journal Of the Electrochemical Society, 161(2014) B75-B80.

[11] G. C. Han, A. Ferranco, X. Z. Feng, Z. C. Chen, H. B. Kraatz, Synthesis, Characterization of Some Ferrocenoyl Cysteine and Histidine Conjugates, and Their Interactions with Some Metal Ions, European Journal Of Inorganic Chemistry, 31(2014) 5337-5347.

[10] S. L. Chen, Z. Liu, G. C. Han, Synthesis, characterization, crystal structure and theoretical approach of (E)-2-[(3-carboxylphenylimino)methylene]phenoxyacetic acid, Journal Of Molecular Structure, 1032(2013) 246-253.

[9] S. L. Chen, Z. Liu, J. Liu, G. C. Han, Y. H. Li, Synthesis, characterization, crystal structure and theoretical approach of Cu(II) complex with 4-{(Z)-[(2-hydroxybenzoyl)hydrazono]methyl}benzoic acid, Journal Of Molecular Structure, 1014(2012) 110-118.

[8] S. L. Chen, Z. Liu, G. C. Han, Synthesis, Crystal Structure and Properties of a Novel Tetranuclear Nickel(II) Complex with Azo-enolic-2-hydroxybenzamide, Chinese Journal Of Structural Chemistry, 31(2012) 1641-1649.

[7] X. Y. Zhou, Z. Liu, M. M. Wang, Y. H. Li, G. C. Han, X. Z. Feng, Polymorphism of flucloxacillin sodium, Pharmazie, 66(2011) 933-935.

[6] H. D. Lu, Y. P. Liu, G. C. Han, Optical and electrochemical properties of ordered macroporous gold array on the ITO surface, Applied Surface Science, 257(2011) 7030-7035.

[5] B. Y. Liu, Z. Liu, G. C. Han, Y. H. Li, Corrosion inhibition and adsorption behavior of 2-((dehydroabietylamine) methyl)-6-methoxyphenol on mild steel surface in seawater, Thin Solid Films, 519(2011) 7836-7844.

[4] B. Y. Liu, Z. Liu, G. C. Han, Y. H. Li, Synthesis, spectroscopic properties, crystal structure and density functional studies of Cu(II) complex with 2-((dehydroabietylamine)methyl)-6-methoxyphenol, Journal Of Molecular Structure, 975(2010) 194-199.

[3] G. C. Han, Y. Peng, Y. Q. Hao, Y. N. Liu, F. M. Zhou, Spectrofluorimetric determination of total free thiols based on formation of complexes of Ce(III) with disulfide bonds, Analytica Chimica Acta, 659(2010) 238-242.

[2] G. C. Han, Y. Ouyang, X. Y. Long, Y. Zhou, M. Li, Y. N. Liu, et al., (Carboxymethyl-Dextran)-Modified Magnetic Nanoparticles Conjugated to Octreotide for MRI Applications, European Journal Of Inorganic Chemistry, (2010) 5455-5461.

[1] G. C. Han, Y. N. Liu, Synthesis, characterization and fluorescent properties of cerium(III) glutathione complex, Luminescence, 25(2010) 389-393.

 

成果奖励

1韩国成(2/7);基于疾病筛查的生物传感器制备机理及基础应用, 广西壮族自治区人民政府, 科技奖-自然科学奖, 省部二等奖, 2021 (陈真诚;韩国成;操良丽;冯小珍;方成;梁永波;赵飞骏)

2韩国成(2/5);高精度生物传感器制备机理及应用, 中国自动化学会, 自然科学奖, 省部二等奖, 2022 (陈真诚;韩国成;操良丽;冯小珍;方成)

3韩国成(1/4);基于CH32的多选择便携式电化学检测装置, 中国生物医学工程学会, 2021年第六届全国大学生生物医学工程创新设计竞赛, 省部一等奖, 2021 (韩国成;安颀祺;连泗峰;周桢凡)

4、韩国成(1/4);基于Cu-MOF构建低成本便携式无酶电化学葡萄糖检测系统, 中国生物医学工程学会, 2023年第八届全国大学生生物医学工程创新设计竞赛, 省部三等奖, 2023 (韩国成;李海翔;薛玉婷;山晨薇)

 

研究方向

生物传感器;电化学分析;化学合成材料